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Fig. 3 Fibronectin is synthesized predominantly by epicardial cells during heart regeneration. (A) Visualization of fn1:mCherry-NTR-expressing cells at 2 dpf. White arrows show fn1:mCherry-NTR+ cells. (B–M) Visualization of fn1:mCherry-NTR+ cells (red) and epicardial cells (tcf21:nucEGFP+; green) in uninjured, 1 and 7 dpa ventricles. Boxed area indicates an enlarged view. Arrows indicate double-positive cells. Dashed line indicates approximate resection plane. Scale bars: 50 μm.
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Reprinted from Developmental Biology, 382(2), Wang, J., Karra, R., Dickson, A.L., and Poss, K.D., Fibronectin is deposited by injury-activated epicardial cells and is necessary for zebrafish heart regeneration, 427-435, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.