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Fig. 5
At 40-50 hpf, the zebrafish heart begins to undergo looping.
(a–c) Compared to 20-30 hpf, WSS across the AV canal is increased by ~9-fold during atrial contraction. However, the magnitude of flow reversal or regurgitation-induced WSS during ventricular contraction decreases by ~33% in comparison with the earlier stages as the AV canal is developing into a valvular structure. (d–i) The ventricle has increased in size when compared to the atrium and absolute values of velocity have increased by 33%, A, atrium; V, ventricle.
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