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Fig. 1

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ZDB-IMAGE-130627-9
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Figures for Kohli et al., 2013
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Fig. 1 Medial and Lateral Angioblasts Originate in Two Distinct Regions, as Observed by ISH Analysis for etv2 Expression (A–L) etv2, flk1/kdrl, and fli1a expression analysis in trunk angioblasts at the 10-, 15-, 18-, and 22-somite stages. etv2 expression is observed in the medial (arrowheads) and lateral (arrows) angioblasts. flk1/kdrl and fli1a expression is initially restricted to the medial angioblasts (B and C) with very weak observed expression in the lateral angioblasts in 15- to 22-somite stage embryos (E–K; F–L). (M–O) etv2 expression in migrating medial angioblasts at the 11- to 14-somite stages. Note that the migration wave progresses in the anterior to posterior direction. The lateral angioblasts migrate later at the 16- to 22-somite stages (G and J). Dorsal view of the trunk and tail region of flat-mounted embryos. Anterior is to the left. Scale bar, 100 μm. See also Figures S1 and S2, and Movies S1, S2, S3, and S4.

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Reprinted from Developmental Cell, 25(2), Kohli, V., Schumacher, J.A., Desai, S.P., Rehn, K., and Sumanas, S., Arterial and venous progenitors of the major axial vessels originate at distinct locations, 196-206, Copyright (2013) with permission from Elsevier. Full text @ Dev. Cell