ZFIN Image: Kumai et al., 2012, Fig. 11

Image

Figure Caption

Fig. 11 The lack of an effect of cortisol on Na⁺ uptake via NCC cells. The microinjection of morpholino against a transcription factor glial cell missing 2 led to a significant reduction in conA positive HR cells (11A, B). mRNA expression of GR was significantly lower in gcm-2 morphants than in sham injected larvae (N = 4–6; 11C). The Na⁺ uptake was significantly elevated in gcm-2 morphants, but no further stimulation was observed following the cortisol treatment (11D; N = 5–6). Data are presented as means ± SEM and an asterisk/different letter denotes significant difference among treatment groups. Scale bars = 200 μm.

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 364(1-2), Kumai, Y., Nesan, D., Vijayan, M.M., and Perry, S.F., Cortisol regulates Na(+) uptake in zebrafish, Danio rerio, larvae via the glucocorticoid receptor, 113-125, Copyright (2012) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.