ZFIN Image: Niu et al., 2012, Fig. S3

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Figure Caption

Fig. S3 The sq198 mutation causes cell cycle arrest in the digestive organs. (A,B) Histochemical staining using anti-phosphorylated histone 3 (anti-pH3) showing cells entering G2 to M phase in wildtype (WT) (A) and mutant (mu) (B) embryos (cells in red). Pan-cadherin was stained to mark the gut epithelia using a monoclonal antibody against Pan-cadherin (Sigma, C1821) in dilution of 1:200 (green). (C) The ratios of pH3-positive cells shown in different tissues were obtained by counting pH3-positive cells against total cells in a specific organ (e.g., intestine) in sections obtained from three wild-type and three mutant embryos, respectively. *: P<0.05; **: P<0.01.

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Acknowledgments

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Reprinted from Developmental Biology, 367(2), Niu, X., Gao, C., Jan Lo, L., Luo, Y., Meng, C., Hong, J., Hong, W., and Peng, J., Sec13 safeguards the integrity of the endoplasmic reticulum and organogenesis of the digestive system in zebrafish, 197-207, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.