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Fig. 7
Pax2/8 misexpression cannot bypass the need for Fgf. (A–F) Dorsal views (anterior up) of pax2a expression at 13 hpf. Embryos were heat shocked at 10 hpf and then incubated in water containing 0.15% DMSO or 30 μM SU5402 and 0.15% DMSO. Genotypes of wild-type and heterozygous transgenic embryos are indicated across the top of the figure. Positions of midbrain–hindbrain boundary (mhb) and otic placode (op) are indicated. Scale bar, 150 μm.
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Reprinted from Developmental Biology, 364(1), Padanad, M.S., Bhat, N., Guo, B., and Riley, B.B., Conditions that influence the response to Fgf during otic placode induction, 1-10, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.