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Fig. 2
Cardionogen Increases Heart Size during Zebrafish Development (A) Chemical structures of the Cardionogen family, including CDNG1/vuc230, CDNG2/vuc198, and CDNG3/vuc247. (B–F) Fluorescent optics displaying untreated control heart (CTL) (B), CDNG1-treated heart (C), CDNG2-treated heart (D), untreated control embryo (CTL) (E), and CDNG1-treated embryo (F) in Tg[cmlc2:EGFP] embryos at 60 hpf. (G and H) Light optics showing control embryos (CTL) (G) and CDNG1-treated embryos (H) at 60 hpf. (B–D) Ventral view; (E–H) lateral view. Red arrow, ventricle; blue arrow, atrium. CDNG1 treatment (30 μM, 5 to 60 hpf).
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