IMAGE

Fig. 2

ID
ZDB-IMAGE-111220-2
Genes
Source
Figures for Doll et al., 2011
Image
Figure Caption

Fig. 2 Kctd12.1 expression is significantly expanded and Kctd12.2 expression significantly decreased throughout larval development in c163 mutants. (A, B, C) In wild-type larvae at 48 hpf, there are 2.1 times as many Kctd12.1-expressing neurons (green) in the left LsDh of the dorsal habenula as in the right. In the MsDh, there are 1.3 times as many Kctd12.2-expressing neurons (red) in the right side as the left. (A′, B′, C′) In c163 mutants, more Kctd12.1+ and fewer Kctd12.2+ neurons are found in the right habenula. (D–F′) At 72 hpf, a similar situation to 48 hpf is observed. Images are 3D reconstructions of 50 μm-thick confocal Z-stacks through the epithalamus. Scale bars represent 10 μm. Significance determined by Student′s T-test (*p < 0.05, **p < 0.01); n > 6. Insets in A–B′, D–E′ show ToPro3 labeling in a single confocal section of the Z-stack.

Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 360(1), Doll, C.A., Burkart, J.T., Hope, K.D., Halpern, M.E., and Gamse, J.T., Subnuclear development of the zebrafish habenular nuclei requires ER translocon function, 44-57, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.