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Fig. 5
Heterozygous kcnh2 zebrafish manifest delayed ventricular repolarization. (a) APs recorded from 48 hpf heterozygous ventricle show increased AP duration compared with wild-type (see Results). (b) Representative electrocardiograms recorded from anesthetized, paralyzed wild-type and heterozygous adult zebrafish. Dashed line indicates duration of QT interval. QT corrected for heart rate (see Materials and Methods) was 396 and 467 msec for the exemplar wild-type and heterozygote, respectively.
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