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Fig. 3 MPZ-MCS3 directs reporter gene expression in relevant tissues in vivo.
Wild-type (A, C, and E) and c.126-1086T>A variant (B, D, and F) containing MPZ-MCS3 were studied for their ability to direct the expression of EGFP in developing zebrafish; expression was analyzed at the indicated developmental stages; EGFP expression is noted in structures consistent with the hindbrain (Hb), midbrain (Mb), forebrain (Fb), descending motor neurons (arrows), lateral line (arrow heads), and oligodendrocytes (boxes and inset in F).
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