ZFIN Image: Hammond et al., 2010, Fig. 3

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Figure Caption

Fig. 3 Ventromedial otic territories are expanded at the expense of dorsolateral domains in shh RNA-injected and ptc1^-/-; lep^-/- embryos. (A-L) Expression of lateral (tbx1), medial (pax2a), dorsal (dlx3b) and ventral (eya1) markers in the zebrafish otic vesicle. Expression domains of dorsolateral markers (tbx1, dlx3b) are reduced relative to ear size in ptc1^-/-; lep^-/- and shh-injected embryos, whereas ventromedial markers (pax2a, eya1) are expanded. Staining in siblings was indistinguishable from wild type. (A-F) Dorsal views; anterior to left, lateral to top. (G-L) Lateral views; anterior to left, dorsal to top. Scale bars: 50 μm (as shown in left-hand image of each trio).

Acknowledgments

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