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Fig. S3 Loss of claudin-5a causes a reduction of brain ventricular volume at 30 h after fertilization. Injection of MOcldn5a significantly reduces the expansion of midbrain (mbv) and hindbrain ventricles (hbv) as assessed by ventricular injection of FITC 70-kDa dextran. White lines indicate different section planes (I and II) of three-dimensional reconstructions of confocal z-stack projections. Coinjection of cldn5a mRNA together with MOcldn5a rescues the brain ventricular expansion defect (Rescue). (Scale bar: 200 μm.)
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Full text @ Proc. Natl. Acad. Sci. USA