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Fig. 11 Ectopic activation of axial (HNF-3β) in response to misexpression of shh is not affected by ethanol treatment. (A and B) Embryos (24 h old) injected with shh mRNA at the one- to two-cell stage and then treated with ethanol (A) or left untreated (B). (C) Uninjected control embryo. When compared to a control embryo (C), shh-injected embryos (A, B) have ectopic expression of axial (HNF-3β) in the anterior neural tube in the presence or absence of ethanol treatment (arrowheads). Orientation of embryos is lateral view with dorsal up and anterior to the left.
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Reprinted from Developmental Biology, 201, Blader, P. and Strähle, U., Ethanol impairs migration of the prechordal plate in the zebrafish embryo, 185-201, Copyright (1998) with permission from Elsevier. Full text @ Dev. Biol.