IMAGE

Fig. 2

ID
ZDB-IMAGE-080904-48
Source
Figures for Kai et al., 2008
Image
Figure Caption

Fig. 2 slb prechordal plate progenitors migrate individually with increased motility and reduced cohesion when Mil function is compromised. (A-I) Time-lapse analysis and tracking of cell movement in migrating prechordal plate progenitors of WT embryos (A-C), slb embryos (D-F) and slb embryos injected with 4.3 ng mil-MO (G-I). Five cells were randomly chosen from each embryo, highlighted in different colours and tracked by merging each starting point to 0 (C,F,I). Twenty-five cells in total were accumulated from five independent experiments, to analyze for speed, persistence and coherence (J). In slb embryos, cell motility was significantly reduced (D-F). In slb embryos injected with mil-MO, the cells showed increased motility, and the cluster of cells appeared to be less coherent (G-I); the cells occasionally popped out from the cluster and travelled individually (H,I, asterisk). Such cell behaviour was never observed in WT embryos. (J) Summary of analysis of parameters: speed, persistence and coherence. Statistically significant differences are indicated (#P<0.05, ##P<0.005).

Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development