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Figure Caption
Fig. 12 Coinjection of the Zf-T and Zf-Pax6.1 double-stranded RNA generates embryos with defective notochords and eyes. (a) Zebrafish embryos injected with double-stranded Zf-T and Zf-Pax6.1 RNA developed significant defects in the eyes and tail. Zebrafish embryos shown are 5 days old. (b) Cross sections of 48-h embryos show that these defects included diminished eye and brain structures and (c) diminished or lacking notochord along with disorganized somites in the tail. Scale bars = 100 μm.
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Reprinted from Developmental Biology, 217(2), Li, Y.X., Farrell, M.J., Liu, R., Mohanty, N., and Kirby, M.L., Double-stranded RNA injection produces null phenotypes in zebrafish, 394-405, Copyright (2000) with permission from Elsevier. Full text @ Dev. Biol.