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Fig. 7 Myc-induced leukemias do not have IgM gene rearrangements. Southern blot analysis of genomic DNA digested with BglII and hybridized with the IgM constant region probe is shown. DNAs are shown from representative Myc-induced leukemias (denoted by numbers) and compared with DNAs from kidney marrow cells harvested from multiple WT control fish (wt). Sizes of DNA standards are noted in kilobases to the right of the blots. The presence of either one or two restriction fragments hybridizing to the IgM probe results from a BglII polymorphic site contained within the gene, not gene rearrangement.
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