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Fig. 6 Myc-induced leukemias have oligoclonal TCR-α gene rearrangement. Southern blot analysis of genomic DNA digested with BglII and hybridized with the TCR-α constant region probe is shown. Representative DNAs of Myc-induced leukemias are shown (numbered) and compared with DNA from the thymus of rag2-GFP control fish (wt-1 and wt-2). The nonrearranged BglII restriction fragment is 8.0 kb; sizes of DNA standards in kilobases are noted to the right of blots.
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Full text @ Proc. Natl. Acad. Sci. USA