Fig. 2

Fig. 2 Expression of dkk1 mRNA during development. (A) High-stage, lateral view, dorsal to the right. (B, C) Sphere stage, lateral view, dorsal to the right (B) and sagittal section (C). (D, E) The 30% epiboly stage, animal pole view, dorsal to the right (D) and dorsal view (E). (F, G) The 50% epiboly stage, animal pole view, dorsal to the right (F) and lateral view, dorsal to the right (G). (H, I, J) Shield stage, animal pole view, dorsal to the right (H), lateral view, dorsal to the right (I), and sagittal section (J). (K, L) The 65% epiboly stage, lateral view, dorsal to the right (K) and dorsal view (L). (M, N, O) The 90% epiboly stage, animal pole view, anterior to the top (M), dorsal view (N), and sagittal section (O). (P, Q) Midsegmentation stage, lateral view, dorsal to the right (P) and animal pole view, anterior to the left (Q). (R1–6) Segmentation stage, lateral views, anterior to the left. dkk1 (purple) and eng3 (red) expression. Arrow heads (1– 4) indicate expression domains of dkk1. R1, 5-somite stage; R2, 7-somite stage; R3, 9-somite stage; R4, 11-somite stage; R5, 13-somite stage; R6, 15-somite stage. (S, T, U, V) 24 hpf, lateral view with dorsal right (S), animal pole view of forebrain region (T) and hindbrain region (U), and lateral view of tail region (V). epi, epiblast; hp, hypoblast; YSL, yolk syncytial layer.