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Fig. 1 locke, swt and kurly mutants develop pronephric cysts. (A–H) 3 dpf, (I–P) 5 dpf. At 3 dpf, locke, swt and kurly mutants are easily identified by their “curly-tail down” phenotype. Panels E–H are higher magnification images of panels A–D, showing the cystic dilations visible under light microscopy. At 5 dpf, the cystic dilations have increased in size shown in panels I–L and magnified in panels M–P. The black arrowheads mark the location of the cysts, posterior to the eye and ear. In general, locke mutants have smaller cysts than swt or kurly.
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Reprinted from Developmental Biology, 314(2), Sullivan-Brown, J., Schottenfeld, J., Okabe, N., Hostetter, C.L., Serluca, F.C., Thiberge, S.Y., and Burdine, R.D., Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants, 261-275, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.