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Fig. 2

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ZDB-IMAGE-071005-37
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Figures for Leung et al., 2005
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Figure Caption

Fig. 2 Hematoxylin and eosin sectioning of WT (A, B) and ChdMO embryos (C, D) at low (A, C) and high-power (B, D) magnification at 24 hpf. In WT embryos, the ICM is only 3–5 cell thick posterior to the yolk extension. The ChdMO embryos had expanded ICM (arrowheads in panel C), which contained a monotonous population of cells with regular and round nuclei and high nuclei to cytoplasm (N/C) ratio. Mitotic figures are easily identified (arrowheads in panel D).

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Reprinted from Developmental Biology, 277(1), Leung, A.Y., Mendenhall, E.M., Kwan, T.T., Liang, R., Eckfeldt, C., Chen, E., Hammerschmidt, M., Grindley, S., Ekker, S.C., and Verfaillie, C.M., Characterization of expanded intermediate cell mass in zebrafish chordin morphant embryos, 235-254, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.