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Fig. 3 Effect of ERRα encoding mRNAs on epiboly. (A–C) Side views of 9 hpf embryos injected with RNA (300 ng/μl) encoding either the dominant-negative ERRαΔAF2 (B) or wild type ERRα (C) compared to the uninjected embryos (A). (D) Dose-dependence of the epiboly delay induced by dominant-negative ERRα mRNA. Wild type or ERRαΔAF2-injected embryos (at the indicated concentrations) were scored as unaffected, mildly or strongly delayed when control embryos reached 80% of epiboly. Number of embryos examined for each condition is indicated below the graph.
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Reprinted from Developmental Biology, 281(1), Bardet, P.L., Horard, B., Laudet, V., and Vanacker, J.M., The ERRalpha orphan nuclear receptor controls morphogenetic movements during zebrafish gastrulation, 102-111, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.