ZFIN Image: Mizoguchi et al., 2006, Fig. 5

Image

Figure Caption

Fig. 5 Either bon or fau/gata5 overexpression can increase the number of cas-expressing endodermal cells in Fgf signaling-inhibited embryos. (A–C) All images are lateral views with anterior to the top. These are magnified views of zebrafish embryos around the marginal region at the 40% epiboly stage (5 hpf). Arrowheads indicate the number of cas-expressing cells from the margin. (A) Overexpression of XFD and oep in WT embryos increases the number of cas-expressing endodermal cells to up to 8 cell diameters from the margin. (B) The cas-expressing endodermal cells were observed to be increased to 11 cell diameters from the margin by co-injection of XFD and oep with bon into WT embryos. (C) Most of the marginal cells within 11 cell diameters from the margin express cas following co-injection of XFD and oep with fau/gata5 into WT embryos.

Acknowledgments

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Reprinted from Developmental Biology, 300(2), Mizoguchi, T., Izawa, T., Kuroiwa, A., and Kikuchi, Y., Fgf signaling negatively regulates Nodal-dependent endoderm induction in zebrafish, 612-622, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.