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Figure Caption
Fig. 2 SU5402 treatment does not affect the expression of either Nodal or Nodal antagonists. (A–H) All images are lateral views with anterior to the top. These are magnified views of zebrafish embryos around the marginal region at the 40% epiboly stage (5 hpf). DMSO, SU5402: oep mRNA was injected into WT embryos, and these injected embryos were subsequently treated with either DMSO or SU5402 from the one cell stage to the 40% epiboly stage. (B, D, F, H) The expression of Nodal genes (cyc and sqt) and Nodal antagonists (lefty1 and lefty2) are not affected by SU5402 treatment.
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Reprinted from Developmental Biology, 300(2), Mizoguchi, T., Izawa, T., Kuroiwa, A., and Kikuchi, Y., Fgf signaling negatively regulates Nodal-dependent endoderm induction in zebrafish, 612-622, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.