ZFIN Image: Walker et al., 2006, Fig. 8

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Figure Caption

Fig. 8 Intermediate arch domains are misspecified in furinA mutants. (A, B) bapx1 expression is strongly reduced in furinA mutants at 48 hpf. (C, D) At 45 hpf, gsc is ectopically expressed in a second arch intermediate domain in furinA mutants. (E, F) barx1 is ectopically expressed in a second arch intermediate domain in furinA mutants at 48 hpf. (G, H) sox9a is ectopically expressed in a second arch intermediate domain in furinA mutants at 48 hpf. (I, J) runx2b is ectopically expressed in a second arch intermediate domain in furinA mutants at 55 hpf. Arrows indicate a second arch intermediate domain in wild-type embryos. Asterisks indicate ectopic expression in a second arch intermediate domain in furinA mutant embryos. a1 and a2 label pharyngeal arch 1 and 2. Scale bars: 50 μm.

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Acknowledgments

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Reprinted from Developmental Biology, 295(1), Walker, M.B., Miller, C.T., Talbot, J.C., Stock, D.W., and Kimmel, C.B., Zebrafish furin mutants reveal intricacies in regulating Endothelin1 signaling in craniofacial patterning, 194-205, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.