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Fig. 6

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ZDB-IMAGE-070815-14
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Figures for Schibler et al., 2007
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Fig. 6 Early patterning of hako mimijj59, mikre uchojj108, and ale uchojj410 mutant ears. The expression of the anterior marker, pax5 (B, H, N, T), does not show any differences between wild-type and mutants. The same is true for pax2a (C, I, O, U), otomp (D, J, P, V), eya1 (E, K, Q, W), and follistatin (fst) (F, L, R, X). The msxc probe (A, G, M, S) is a marker of cristae. Its expression is absent in both mikre uchojj108 (M), and hako mimijj59 (G) mutants, but remains wild-type in ale uchojj410 (S). pax5, pax2a, otomp, and eya1 expression patterns were evaluated at 24 hpf, the fst expression at 36 hpf, and msxc at 48 hpf. In the pax2a column, expression is shown from the dorsal side. In all other columns, anterior is left and dorsal is up. Images of mxsc and otomp are at the same magnification. Likewise, the images of pax5, pax2a, eya1, and fst were collected at the same magnification. Scale bars equal 50 &mum.

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Reprinted from Mechanisms of Development, 124(7-8), Schibler, A., and Malicki, J., A screen for genetic defects of the zebrafish ear, 592-604, Copyright (2007) with permission from Elsevier. Full text @ Mech. Dev.