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Fig. 4

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ZDB-IMAGE-070801-4
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Figures for Jin et al., 2007
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Fig. 4 Mutations affecting vascular tube formation. (A) Epifluorescent micrograph of 36 hpf Tg(flk1:EGFP)s843 embryo in lateral view (A). White line marks the location of the transverse sections shown in panels B to F. (B–G) Transverse sections of wild-type (B), sih/cmc2 MO injected (C), sols828 mutant (D), mtss233 mutant (E), logs231 mutant (F), and psns634 mutant (G) Tg(flk1:EGFP)s843 embryos. Lack of circulation does not affect vascular lumen formation (C). Note changes in the number of vascular lumens in sols828 and mtss233 mutant embryos, and in the size and shape of the vascular lumens in logs231 and psns634 mutant embryos.

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Reprinted from Developmental Biology, 307(1), Jin, S.W., Herzog, W., Santoro, M.M., Mitchell, T.S., Frantsve, J., Jungblut, B., Beis, D., Scott, I.C., D'Amico, L.A., Ober, E.A., Verkade, H., Field, H.A., Chi, N.C., Wehman, A.M., Baier, H., and Stainier, D.Y., A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos, 29-42, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.