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Fig. 8 Effects of tiggy winkle (twhh) ectopic expression on eye development in wild-type (A, B) and trim209 mutant embryos (C–E) at 48 hpf. twhh mRNA (0.1 ng) was injected into zebrafish embryos at the one- to eight-cell stage. In injected wild-type and mutant embryos unilateral or bilateral reduction of retina and pigment epithelium was observed. Notably synopthalmia and cyclopia were still observed in affected mutant embryos (D, E). Bar, 63 um.
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Reprinted from Developmental Biology, volume 203, Marlow, F., Zwartkruis, F., Malicki, J., Neuhauss, S.C.F., Abbas, L., Weaver, M., Driever, W., and Solnica-Krezel, L., Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish, 382-399, Copyright 1998, with permission from Elsevier.
Reprinted from Developmental Biology, 203, Marlow, F., Zwartkruis, F., Malicki, J., Neuhauss, S.C.F., Abbas, L., Weaver, M., Driever, W., and Solnica-Krezel, L., Functional interactions of genes mediating convergent extension, knypek and trilobite, during the partitioning of the eye primordium in zebrafish, 382-399, Copyright (1998) with permission from Elsevier. Full text @ Dev. Biol.