ZFIN Image: Feldner et al., 2005, Fig. 7

Image

Figure Caption

Fig. 7 Subthreshold concentrations of neuropilin-1a (NRP1a) morpholino1 in combination with vascular endothelial growth factor (VEGF), semaphorin (sema) 3A1, or sema3A2 morpholinos induce aberrant growth of motor nerves. Lateral views of anti-tubulin-labeled whole-mounted 24 hours postfertilization (hpf) embryos at mid-trunk levels are shown (rostral is left). A-E: Combinations of NRP1a morpholino1 with VEGF (A) or sema3A2 (D) morpholinos induce aberrant motor nerve branching (arrows in A,D), whereas displaced neurons in the path of the ventral motor nerve (arrows in B,C,E) occur after combination of NRP1a morpholino1 with VEGF (B), sema3A1 (C), or sema3A2 (E) morpholinos. Scale bar = 25 μm in E (applies to A-E).

Acknowledgments

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