Gene

svila

ID

ZDB-GENE-990706-5

Name

supervillin a

Symbol

svila Nomenclature History

Previous Names

svil
sb:cb867
wu:fd05a09
zmp:0000000648 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have actin filament binding activity. Predicted to be involved in cytoskeleton organization. Is expressed in several structures, including adaxial cell; cardiovascular system; musculature system; optic vesicle; and sensory system. Orthologous to human SVIL (supervillin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb867 (17 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Deo et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With svila Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
myofibrillar myopathy 10	Alliance	Myofibrillar myopathy 10	619040

Associated With svila Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003128	Villin headpiece
Domain	IPR007123	Gelsolin-like domain
Family	IPR007122	Villin/Gelsolin
Homologous_superfamily	IPR029006	ADF-H/Gelsolin-like domain superfamily
Homologous_superfamily	IPR036886	Villin headpiece domain superfamily

Domain Details Per Protein

Protein	Length	ADF-H/Gelsolin-like domain superfamily	Gelsolin-like domain	Villin/Gelsolin	Villin headpiece	Villin headpiece domain superfamily
UniProtKB:A0A8M9Q864 InterPro	2239
UniProtKB:A0A8M9QII8 InterPro	2264
UniProtKB:A0A8M9QE30 InterPro	2208
UniProtKB:A0A8M9PW23 InterPro	2241
UniProtKB:A0A8M9QIJ4 InterPro	1847
UniProtKB:A0A8M9QMC6 InterPro	1919
UniProtKB:Q38HW9 InterPro	1763
UniProtKB:F1Q6K8 InterPro	1763

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	svila-207 (1) Ensembl	Havana	750 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	svila-201 (1) Ensembl	Havana	6407 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	svila-202 (1) Ensembl	Havana	511 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	svila-203 (1) Ensembl	Havana	2851 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	svila-204 (1) Ensembl	Havana	553 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	svila-205 (1) Ensembl	Havana	896 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	svila-005 (1) Ensembl	Havana	378 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations