Gene
foxa1
- ID
- ZDB-GENE-990415-78
- Name
- forkhead box A1
- Symbol
- foxa1 Nomenclature History
- Previous Names
-
- fkd7 (1)
- forkhead-7
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Enables transcription cis-regulatory region binding activity. Involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Acts upstream of or within axial mesoderm morphogenesis. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; chordo neural hinge; digestive system; endoderm; and liver primordium. Orthologous to human FOXA1 (forkhead box A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 61 figures from 52 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65744 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Lai et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018122 | Fork head domain conserved site1 |
Conserved_site | IPR030456 | Fork head domain conserved site 2 |
Domain | IPR001766 | Fork head domain |
Domain | IPR013638 | Fork-head N-terminal |
Domain | IPR018533 | Forkhead box protein, C-terminal |
Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Forkhead box protein, C-terminal | Fork head domain | Fork head domain conserved site1 | Fork head domain conserved site 2 | Fork-head N-terminal | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:O73783
|
424 | |||||||
UniProtKB:Q6P0C9
|
427 | |||||||
UniProtKB:Q800Q3
|
427 |
Interactions and Pathways
No data available
Plasmids
No data available