Gene

nr2f2

ID
ZDB-GENE-990415-252
Name
nuclear receptor subfamily 2, group F, member 2
Symbol
nr2f2 Nomenclature History
Previous Names
  • COUP-TFII (1)
  • COUPTFbeta (1)
  • svp40 (1)
  • svp[40] (1)
  • wu:fc94g08 (1)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II regulatory region sequence-specific DNA binding activity; nuclear receptor activity; and retinoic acid binding activity. Involved in circulatory system development and cranial skeletal system development. Predicted to localize to nucleus. Is expressed in several structures, including brain; head; hindbrain neural keel; midbrain neural tube; and neural crest cell. Orthologous to human NR2F2 (nuclear receptor subfamily 2 group F member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
28 figures from 14 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nr2f2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
46,XX sex reversal 5 Alliance 46,XX sex reversal 5 618901
Congenital heart defects, multiple types, 4 615779
Associated With nr2f2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:Q91430 422
UniProtKB:F1Q6P8 140
UniProtKB:B3DGQ7 428
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations