Gene
pou4f3
- ID
- ZDB-GENE-990415-24
- Name
- POU class 4 homeobox 3
- Symbol
- pou4f3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in brain development. Predicted to localize to cytoplasm and nuclear chromatin. Is expressed in auditory receptor cell. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 15 and autosomal dominant nonsyndromic deafness 52. Orthologous to human POU4F3 (POU class 4 homeobox 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Deafness, autosomal dominant 15 | 602459 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Homeobox, conserved site | Lambda repressor-like, DNA-binding domain superfamily | POU domain | POU-specific domain |
---|---|---|---|---|---|
UniProtKB:Q90435
|
331 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
pou4f3-201
(1)
|
Havana | 996 nt |
Interactions and Pathways
No data available
Plasmids
No data available