Gene
hoxd10a
- ID
- ZDB-GENE-990415-116
- Name
- homeobox D10a
- Symbol
- hoxd10a Nomenclature History
- Previous Names
-
- hoxd-10
- hoxd10
- z-82
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in caudal fin; mesenchyme; oocyte; pectoral fin bud; and pectoral fin field. Human ortholog(s) of this gene implicated in congenital vertical talus. Orthologous to human HOXD10 (homeobox D10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital vertical talus | Alliance | Charcot-Marie-Tooth disease, foot deformity of | 192950 |
| congenital vertical talus | Alliance | Vertical talus, congenital | 192950 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeobox protein Hox-A10/abdominal-B-like | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q90469 | InterPro | 332 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hoxd10a-201
(1)
|
Ensembl | 1,650 nt |
Interactions and Pathways
No data available
Plasmids