Gene

pax9

ID
ZDB-GENE-980526-399
Name
paired box 9
Symbol
pax9 Nomenclature History
Previous Names
  • etID309776.17 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Enables sequence-specific DNA binding activity. Involved in anatomical structure development and regulation of transcription by RNA polymerase II. Acts upstream of or within roof of mouth development. Predicted to be located in nucleus. Is expressed in several structures, including head mesenchyme; neural tube; olfactory region; oral ectoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human PAX9 (paired box 9).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
26 figures from 17 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pax9 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
tooth agenesis Alliance Tooth agenesis, selective, 3 604625
Associated With pax9 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001523 Paired domain
Domain IPR043182 Paired DNA-binding domain
Family IPR033204 Paired box protein PAX9
Family IPR043565 PAX family
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Homeobox-like domain superfamily Paired box protein PAX9 Paired DNA-binding domain Paired domain PAX family Winged helix-like DNA-binding domain superfamily
UniProtKB:K7DYI1 15
UniProtKB:Q98866 270
UniProtKB:Q98865 343
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations