Gene
pax9
- ID
- ZDB-GENE-980526-399
- Name
- paired box 9
- Symbol
- pax9 Nomenclature History
- Previous Names
-
- etID309776.17 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Enables sequence-specific DNA binding activity. Involved in anatomical structure development and regulation of transcription by RNA polymerase II. Acts upstream of or within roof of mouth development. Predicted to be located in nucleus. Is expressed in several structures, including head mesenchyme; neural tube; olfactory region; oral ectoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human PAX9 (paired box 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 26 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu604 (12 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| tooth agenesis | Alliance | Tooth agenesis, selective, 3 | 604625 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001523 | Paired domain |
| Domain | IPR043182 | Paired DNA-binding domain |
| Family | IPR033204 | Paired box protein PAX9 |
| Family | IPR043565 | PAX family |
| Homologous_superfamily | IPR009057 | Homeobox-like domain superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Homeobox-like domain superfamily | Paired box protein PAX9 | Paired DNA-binding domain | Paired domain | PAX family | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:K7DYI1
|
15 | ||||||
|
UniProtKB:Q98866
|
270 | ||||||
|
UniProtKB:Q98865
|
343 |
Interactions and Pathways
No data available
Plasmids
No data available