Gene

pax9

ID

ZDB-GENE-980526-399

Name

paired box 9

Symbol

pax9 Nomenclature History

Previous Names

etID309776.17 (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Exhibits sequence-specific DNA binding activity. Involved in hard palate development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in tooth agenesis. Is expressed in several structures, including head mesenchyme; neural tube; olfactory region; oral ectoderm; and pharyngeal arch. Orthologous to human PAX9 (paired box 9).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

31 figures from 19 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

eu604 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pax9 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
tooth agenesis	Alliance	Tooth agenesis, selective, 3	604625

Associated With pax9 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001523	Paired domain
Domain	IPR043182	Paired DNA-binding domain
Family	IPR043565	PAX family
Homologous_superfamily	IPR009057	Homeobox-like domain superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Homeobox-like domain superfamily	Paired DNA-binding domain	Paired domain	PAX family	Winged helix-like DNA-binding domain superfamily
UniProtKB:Q98865 InterPro	343
UniProtKB:Q98866 InterPro	270

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pax9-201 (1) Ensembl	Havana	1763 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pax9-202 (1) Ensembl	Havana	1903 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pax9-203 (1) Ensembl	Havana	759 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations