Gene
pax9
- ID
- ZDB-GENE-980526-399
- Name
- paired box 9
- Symbol
- pax9 Nomenclature History
- Previous Names
-
- etID309776.17 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Enables sequence-specific DNA binding activity. Acts upstream of or within defense response to Gram-positive bacterium; regulation of neutrophil differentiation; and roof of mouth development. Predicted to be located in nucleus. Is expressed in several structures, including axial blood vessel; digestive system; hematopoietic system; oral ectoderm; and pharyngeal arch. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human PAX9 (paired box 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 33 figures from 20 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu604 (12 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| tooth agenesis | Alliance | Tooth agenesis, selective, 3 | 604625 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Paired DNA-binding domain | Paired domain | PAX family | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q98865 | InterPro | 343 | |||||
| UniProtKB:Q98866 | InterPro | 270 |
Interactions and Pathways
No data available
Plasmids
No data available