Gene

cahz

ID
ZDB-GENE-980526-39
Name
carbonic anhydrase
Symbol
cahz Nomenclature History
Previous Names
  • cah
  • ca2b (1)
  • cb588 (1)
  • id:ibd5016 (1)
  • wu:cegs2190
  • wu:fj65c09
  • zCA2-like b (1)
  • zCAb (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Enables carbonate dehydratase activity. Involved in one-carbon metabolic process. Acts upstream of or within carbon dioxide transport and hypotonic salinity response. Is expressed in several structures, including hematopoietic system; mesoderm; nervous system; pleuroperitoneal region; and presumptive blood. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 3 and osteopetrosis. Orthologous to several human genes including CA2 (carbonic anhydrase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
33 figures from 16 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Gilmour et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cahz Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive osteopetrosis 3 Alliance Osteopetrosis, autosomal recessive 3, with renal tubular acidosis 259730
Associated With cahz Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018338 Carbonic anhydrase, alpha-class, conserved site
Domain IPR001148 Alpha carbonic anhydrase domain
Family IPR023561 Carbonic anhydrase, alpha-class
Homologous_superfamily IPR036398 Alpha carbonic anhydrase domain superfamily
Domain Details Per Protein
Protein Length Alpha carbonic anhydrase domain Alpha carbonic anhydrase domain superfamily Carbonic anhydrase, alpha-class Carbonic anhydrase, alpha-class, conserved site
UniProtKB:Q92051 260
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations