Gene

pou3f3b

ID
ZDB-GENE-980526-140
Name
POU class 3 homeobox 3b
Symbol
pou3f3b Nomenclature History
Previous Names
  • pou1
  • pou23
  • zp23
  • fb92g06
  • wu:fb92g06 (1)
  • zfpou1 (1)
  • zp23pou
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in X-linked deafness 2. Is expressed in nervous system; neural rod; otic vesicle; pronephric duct; and spinal cord neural tube. Orthologous to several human genes including POU3F3 (POU class 3 homeobox 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Barske et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pou3f3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Snijders Blok-Fisher syndrome 618604
Associated With pou3f3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR000327 POU-specific domain
Domain IPR001356 Homeobox domain
Domain IPR013847 POU domain
Family IPR016362 POU-domain transcription factor, class 3
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR010982 Lambda repressor-like, DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Lambda repressor-like, DNA-binding domain superfamily POU domain POU-domain transcription factor, class 3 POU-specific domain
UniProtKB:P79745 443
UniProtKB:A0A8M2BFZ4 440
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations