ZFIN is now using GRCz12tu for Genomic Data
Gene
gabra2b
- ID
- ZDB-GENE-171102-1
- Name
- gamma-aminobutyric acid type A receptor subunit alpha2b
- Symbol
- gabra2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable chloride channel activity; extracellular ligand-gated monoatomic ion channel activity; and transmembrane signaling receptor activity. Predicted to contribute to GABA-A receptor activity. Predicted to be involved in GABAergic synaptic transmission; chloride transmembrane transport; and inhibitory synapse assembly. Predicted to act upstream of or within chloride transport and monoatomic ion transmembrane transport. Predicted to be located in postsynaptic membrane. Predicted to be part of GABA-A receptor complex. Predicted to be active in dendrite membrane and postsynapse. Is expressed in brain; cerebellum; diencephalon; optic tectum; and telencephalon.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| alcohol dependence | Alliance | {Alcohol dependence, susceptibility to} | 103780 |
| developmental and epileptic encephalopathy 78 | Alliance | Developmental and epileptic encephalopathy 78 | 618557 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M9PZF4 | InterPro | 399 |
| UniProtKB:A0AC58H9A5 | InterPro | 451 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gabra2b-201
(1)
|
Ensembl | 1,200 nt | ||
| mRNA |
gabra2b-202
(1)
|
Ensembl | 1,405 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers