Gene
iqgap3
- ID
- ZDB-GENE-160226-1
- Name
- IQ motif containing GTPase activating protein 3
- Symbol
- iqgap3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Involved in cell motility and convergent extension involved in gastrulation. Is expressed in digestive system; pectoral fin bud; pharyngeal arch; sensory system; and ventricular zone. Orthologous to human IQGAP3 (IQ motif containing GTPase activating protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Fang et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Fang et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR000048 | IQ motif, EF-hand binding site |
| Conserved_site | IPR023152 | Ras GTPase-activating protein, conserved site |
| Domain | IPR000593 | RasGAP protein, C-terminal |
| Domain | IPR001202 | WW domain |
| Domain | IPR001715 | Calponin homology domain |
| Domain | IPR001936 | Ras GTPase-activating domain |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
| Protein | Length | Calponin homology domain | CH domain superfamily | IQ motif, EF-hand binding site | RasGAP protein, C-terminal | Ras GTPase-activating domain | Ras GTPase-activating protein, conserved site | Rho GTPase activation protein | WW domain |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0F7EVQ6
|
1639 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available