ZFIN is now using GRCz12tu for Genomic Data
Gene
areg
- ID
- ZDB-GENE-141216-239
- Name
- amphiregulin
- Symbol
- areg Nomenclature History
- Previous Names
-
- si:ch73-49h18.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable epidermal growth factor receptor binding activity and growth factor activity. Predicted to be involved in epidermal growth factor receptor signaling pathway; positive regulation of cell population proliferation; and positive regulation of mitotic nuclear division. Predicted to be located in membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human AREG (amphiregulin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like domain |
|---|---|---|---|
| UniProtKB:F1RB57 | InterPro | 223 | |
| UniProtKB:A0A8M3AS34 | InterPro | 223 | |
| UniProtKB:A0AB32THP2 | InterPro | 191 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers