Gene
sco1
- ID
- ZDB-GENE-140909-1
- Name
- synthesis of cytochrome C oxidase 1
- Symbol
- sco1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease and mitochondrial complex IV deficiency nuclear type 4. Orthologous to human SCO1 (synthesis of cytochrome C oxidase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sun et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa8760 | Allele with one point mutation | Unknown | Unknown | ENU |
1 - 1 of 1
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Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 4 | Alliance | Mitochondrial complex IV deficiency, nuclear type 4 | 619048 |
1 - 1 of 1
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Copper chaperone SCO1/SenC | Thioredoxin-like superfamily |
|---|---|---|---|---|
| UniProtKB:E7FD19 | InterPro | 318 |
1 - 1 of 1
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available