Gene
xcr1b.3
- ID
- ZDB-GENE-140730-2
- Name
- chemokine (C motif) receptor 1b, duplicate 3
- Symbol
- xcr1b.3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in brain. Orthologous to human XCR1 (X-C motif chemokine receptor 1).
- Genome Resources
-
- Alliance (1)
- Gene:100329726 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | C-C chemokine receptor type 1-9-like | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
| UniProtKB:E7F7S2 | InterPro | 370 | |||
| UniProtKB:A0A8M1REM0 | InterPro | 370 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
No data available
No data available
- Comparative Orthology
- Alliance
- Rougeot, J., Torraca, V., Zakrzewska, A., Kanwal, Z., Jansen, H.J., Sommer, F., Spaink, H.P., Meijer, A.H. (2019) RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection. Frontiers in immunology. 10:832
- Blaser, B.W., Moore, J.L., Hagedorn, E.J., Li, B., Riquelme, R., Lichtig, A., Yang, S., Zhou, Y., Tamplin, O.J., Binder, V., Zon, L.I. (2017) CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of experimental medicine. 214(4):1011
- Nomiyama, H., Osada, N., and Yoshie, O. (2013) Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history. Genes to cells : devoted to molecular & cellular mechanisms. 18(1):1-16
- Liu, Y., Chang, M.X., Wu, S.G., and Nie, P. (2009) Characterization of C-C chemokine receptor subfamily in teleost fish. Molecular immunology. 46(3):498-504
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