Gene
slitrk4
- ID
- ZDB-GENE-140303-1
- Name
- SLIT and NTRK-like family, member 4
- Symbol
- slitrk4 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to be involved in axonogenesis and positive regulation of synapse assembly. Predicted to act upstream of or within regulation of presynapse assembly. Predicted to be located in membrane. Predicted to be active in glutamatergic synapse. Is expressed in central nervous system and retina. Orthologous to human SLITRK4 (SLIT and NTRK like family member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Round et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cysteine-rich flanking region, C-terminal | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype |
|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IYE6 | InterPro | 830 | ||||
| UniProtKB:A0A8M9QKW6 | InterPro | 769 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slitrk4-201
(1)
|
Ensembl | 3,472 nt | ||
| mRNA |
slitrk4-202
(1)
|
Ensembl | 4,819 nt | ||
| mRNA |
slitrk4-203
(1)
|
Ensembl | 2,493 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-263P22 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005157225 (1) | 4999 nt | ||
| Genomic | GenBank:CR847498 (2) | 168227 nt | ||
| Polypeptide | UniProtKB:A0A0R4IYE6 (1) | 830 aa |
No data available
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Round, J., Ross, B., Angel, M., Shields, K., and Lom, B. (2014) Slitrk gene duplication and expression in the developing zebrafish nervous system. Developmental Dynamics : an official publication of the American Association of Anatomists. 243(2):339-49
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