adgrg2a

ID

ZDB-GENE-140106-206

Name

adhesion G protein-coupled receptor G2a

Symbol

adgrg2a Nomenclature History

Previous Names

gpr64
gpr64a
zmp:0000001246 (1)

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; heart; integument; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in X-linked congenital bilateral absence of vas deferens. Orthologous to human ADGRG2 (adhesion G protein-coupled receptor G2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Harty et al., 2015

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adgrg2a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
X-linked congenital bilateral absence of vas deferens	Alliance	Congenital bilateral absence of vas deferens, X-linked	300985

Associated With adgrg2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:E7F4F2	InterPro	947
UniProtKB:A0A8M2B9R8	InterPro	2289
UniProtKB:A0AC58IRG8	InterPro	4181
UniProtKB:A0AC58IRH3	InterPro	5834
UniProtKB:A0AC58IRH5	InterPro	5815
UniProtKB:A0AC58IRH7	InterPro	4207