Gene

adgrg2a

ID
ZDB-GENE-140106-206
Name
adhesion G protein-coupled receptor G2a
Symbol
adgrg2a Nomenclature History
Previous Names
  • gpr64
  • gpr64a
  • zmp:0000001246 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; heart; integument; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in X-linked congenital bilateral absence of vas deferens. Orthologous to human ADGRG2 (adhesion G protein-coupled receptor G2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Harty et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adgrg2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
X-linked congenital bilateral absence of vas deferens Alliance Congenital bilateral absence of vas deferens, X-linked 300985
Associated With adgrg2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000203 GPS motif
Conserved_site IPR017983 GPCR, family 2, secretin-like, conserved site
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Domain IPR017981 GPCR, family 2-like, 7TM
Family IPR000832 GPCR, family 2, secretin-like
Homologous_superfamily IPR046338 GAIN domain superfamily
Domain Details Per Protein
Protein Additional Resources Length GAIN domain superfamily GPCR, family 2-like, 7TM GPCR, family 2, secretin-like GPCR, family 2, secretin-like, conserved site GPCR, rhodopsin-like, 7TM GPS motif
UniProtKB:E7F4F2 InterPro 947
UniProtKB:A0A8M2B9R8 InterPro 2289
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA adgrg2a-201 (1) Ensembl 3,114 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations