ZFIN is now using GRCz12tu for Genomic Data
Gene
opn7a
- ID
- ZDB-GENE-140106-15
- Name
- opsin 7, group member a
- Symbol
- opn7a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable G protein-coupled photoreceptor activity. Acts upstream of or within phototransduction. Predicted to be located in membrane. Predicted to be active in photoreceptor outer segment and plasma membrane. Is expressed in several structures, including brain; digestive system; eye; heart; and testis.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Davies et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa18114 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G-protein coupled receptor opsins | G protein-coupled receptor, rhodopsin-like | Peropsin | Visual pigments (opsins) retinal binding site |
|---|---|---|---|---|---|---|---|
| UniProtKB:F1RAF0 | InterPro | 455 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
No data available
No data available
- Genome Browsers
| Type | Accession # | Genome Assembly | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001316948 (1) | 1368 nt | ||
| Genomic | GenBank:JBMGRA010000020 (1) | |||
| Polypeptide | UniProtKB:F1RAF0 (1) | 455 aa |
- Comparative Orthology
- Alliance
No data available
- Saiz, N., Alonso-Gómez, Á.L., Bustamante-Martínez, S., de Pedro, N., Delgado, M.J., Isorna, E. (2024) Is there direct photoentrainment in the goldfish liver? Wavelength-dependent regulation of clock genes and investigation of the opsin 7 family. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. :
- Liang, Q., Afriyie, G., Chen, Z., Xu, Z., Dong, Z., Wang, Z., Guo, Y. (2021) Analysis of Opsin Gene Family of Crimson Snapper (Lutjanus erythropterus). Gene. 807:145960
- Steindal, I.A.F., Whitmore, D. (2020) Zebrafish Circadian Clock Entrainment and the Importance of Broad Spectral Light Sensitivity. Frontiers in Physiology. 11:1002
- Sato, K., Yamashita, T., Haruki, Y., Ohuchi, H., Kinoshita, M., Shichida, Y. (2016) Two UV-Sensitive Photoreceptor Proteins, Opn5m and Opn5m2 in Ray-Finned Fish with Distinct Molecular Properties and Broad Distribution in the Retina and Brain. PLoS One. 11:e0155339
- Davies, W.I., Tamai, T.K., Zheng, L., Fu, J.K., Rihel, J., Foster, R.G., Whitmore, D., Hankins, M.W. (2015) An extended family of novel vertebrate photopigments is widely expressed and displays a diversity of function. Genome research. 25(11):1666-79
- Manchenkov, T., Pasillas, M.P., Haddad, G.G., Imam, F.B. (2015) Novel Genes Critical for Hypoxic Preconditioning in Zebrafish Are Regulators of Insulin and Glucose Metabolism. G3 (Bethesda). 5(6):1107-16
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