Gene

phlpp1

ID

ZDB-GENE-131127-271

Name

PH domain and leucine rich repeat protein phosphatase 1

Symbol

phlpp1 Nomenclature History

Previous Names

si:ch73-40a17.1

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in membrane and nucleus. Predicted to be active in cytoplasm. Orthologous to human PHLPP1 (PH domain and leucine rich repeat protein phosphatase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With phlpp1 Human Ortholog

No data available

Associated With phlpp1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001932	PPM-type phosphatase-like domain
Domain	IPR055071	PHLPP-like, RA domain
Family	IPR050216	Leucine-rich repeat domain-containing protein
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036457	PPM-type phosphatase-like domain superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype

Domain Details Per Protein

Protein	Additional Resources	Length	Leucine-rich repeat	Leucine-rich repeat domain-containing protein	Leucine-rich repeat domain superfamily	Leucine-rich repeat, typical subtype	PHLPP-like, RA domain	PPM-type phosphatase-like domain	PPM-type phosphatase-like domain superfamily
UniProtKB:A0A8M3AN82	InterPro	1483

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	phlpp1-201 (1) Ensembl	Ensembl	6,123 nt	Select Tool ZFIN BLAST
mRNA	phlpp1-202 (1) Ensembl	Ensembl	4,284 nt	Select Tool ZFIN BLAST
mRNA	phlpp1-203 (1) Ensembl	Ensembl	4,281 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations