Gene
ccser2a
- ID
- ZDB-GENE-131121-492
- Name
- coiled-coil serine-rich protein 2a
- Symbol
- ccser2a Nomenclature History
- Previous Names
-
- si:ch73-34j14.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable microtubule binding activity. Predicted to be involved in microtubule bundle formation. Predicted to be active in microtubule cytoskeleton. Orthologous to human CCSER2 (coiled-coil serine rich protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Targeting Reagent | Created Alleles | Citations |
---|---|---|
CRISPR1-ccser2a | (2) | |
CRISPR2-ccser2a | (2) | |
MO1-ccser2a | N/A | Zang et al., 2025 |
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Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Family | IPR029627 | Serine-rich coiled-coil domain-containing protein |
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Domain Details Per Protein
Protein | Additional Resources | Length | Serine-rich coiled-coil domain-containing protein |
---|---|---|---|
UniProtKB:E7F0A9 | InterPro | 967 | |
UniProtKB:A0A8M9PEV7 | InterPro | 805 | |
UniProtKB:A0A8M9PCU6 | InterPro | 802 | |
UniProtKB:A0A8M2B5E7 | InterPro | 805 | |
UniProtKB:A0A8M9Q2J6 | InterPro | 967 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
ccser2a-201
(1)
|
Ensembl | 7,378 nt | ||
mRNA |
ccser2a-202
(1)
|
Ensembl | 918 nt | ||
mRNA |
ccser2a-203
(1)
|
Ensembl | 4,417 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH73-34J14 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_068218879 (1) | 3546 nt | ||
Genomic | GenBank:BX284692 (1) | 162969 nt | ||
Polypeptide | UniProtKB:A0A8M9Q2J6 (1) | 967 aa |
- Zang, J.L., Gibson, D., Zheng, A.M., Shi, W., Gillies, J.P., Stein, C., Drerup, C.M., DeSantis, M.E. (2025) CCSer2 gates dynein activity at the cell periphery. The Journal of cell biology. 224:
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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