Gene

tdg.2

ID
ZDB-GENE-131121-30
Name
thymine DNA glycosylase, tandem duplicate 2
Symbol
tdg.2 Nomenclature History
Previous Names
  • tgd.2
  • si:ch211-68a17.8 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable pyrimidine-specific mismatch base pair DNA N-glycosylase activity and uracil DNA N-glycosylase activity. Predicted to be involved in base-excision repair, AP site formation. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human TDG (thymine DNA glycosylase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa39480Allele with one point mutationUnknownSplice SiteENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa39481Allele with one point mutationUnknownSplice SiteENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With tdg.2 Human Ortholog
No data available
Associated With tdg.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005122 Uracil-DNA glycosylase-like
Family IPR015637 Uracil DNA glycosylase family 2
Homologous_superfamily IPR036895 Uracil-DNA glycosylase-like domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length Uracil DNA glycosylase family 2 Uracil-DNA glycosylase-like Uracil-DNA glycosylase-like domain superfamily
UniProtKB:X1WBY3 InterPro 400
UniProtKB:E7F5Y8 InterPro 399
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 25
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tdg.2-201 (1)
Ensembl
Ensembl 5,370 nt
ZFIN BLAST
mRNA tdg.2-202 (1)
Ensembl
Ensembl 760 nt
ZFIN BLAST
mRNA tdg.2-203 (1)
Ensembl
Ensembl 4,349 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-68A17ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_009297976 (1)
ZFIN BLASTNCBI BLASTMegaBLASTEnsemblUCSC BLAT
GenomicGenBank:CR391963 (1)107587 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:X1WBY3 (1)400 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanTDG12
Amino acid sequence comparison (1)
Nucleotide sequence comparison (1)
Conserved genome location (synteny) (1)
MouseTdg10
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
TSV
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