Gene

ptprjb.2

ID

ZDB-GENE-131120-137

Name

protein tyrosine phosphatase receptor type Jb, tandem duplicate 2

Symbol

ptprjb.2 Nomenclature History

Previous Names

si:dkey-5l8.2

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in negative regulation of MAP kinase activity and protein dephosphorylation. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptprjb.2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
colorectal cancer	Alliance	Colon cancer, somatic	114500
		Thrombocytopenia 10	620484

Associated With ptprjb.2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like

Domain Details Per Protein

Protein	Length	Protein-tyrosine phosphatase, active site	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Tyrosine-specific protein phosphatase, PTPase domain	Tyrosine-specific protein phosphatases domain
UniProtKB:A0A8M9P6I8 InterPro	263

Transcripts

Genome Browsers

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ptprjb.2-201 (1) Ensembl	Havana	1042 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations