Gene
lgals9l6
- ID
- ZDB-GENE-131119-90
- Name
- lectin, galactoside-binding, soluble, 9 (galectin 9)-like 6
- Symbol
- lgals9l6 Nomenclature History
- Previous Names
-
- si:ch211-209m20.9
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable carbohydrate binding activity and galactoside binding activity. Predicted to be involved in negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of type II interferon production; and positive regulation of gene expression. Predicted to be active in cytosol and nucleus. Orthologous to human LGALS9 (galectin 9); LGALS9B (galectin 9B); and LGALS9C (galectin 9C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Rajshekar et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa5791 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Concanavalin A-like lectin/glucanase domain superfamily | Galectin, carbohydrate recognition domain | Galectin-like |
|---|---|---|---|---|---|
| UniProtKB:A0A8M1QV52 | InterPro | 281 | |||
| UniProtKB:A0AB32T3V5 | InterPro | 323 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lgals9l6-201
(1)
|
Ensembl | 1,064 nt | ||
| mRNA |
lgals9l6-202
(1)
|
Ensembl | 981 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-209M20 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068213631 (1) | 1024 nt | ||
| Genomic | GenBank:BX000438 (1) | 195087 nt | ||
| Polypeptide | UniProtKB:A0AB32T3V5 (1) | 323 aa |
No data available
- Rajshekar, S., Yao, J., Arnold, P.K., Payne, S.G., Zhang, Y., Bowman, T.V., Schmitz, R.J., Edwards, J.R., Goll, M. (2018) Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome. eLIFE. 7:
- Zhou, S., Zhao, H., Thongda, W., Zhang, D., Su, B., Yu, D., Peatman, E., Li, C. (2016) Galectins in channel catfish, Ictalurus punctatus: Characterization and expression profiling in mucosal tissues. Fish & shellfish immunology. 49:324-35
- Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41
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