Gene
mast1b
- ID
- ZDB-GENE-131025-2
- Name
- microtubule associated serine/threonine kinase 1b
- Symbol
- mast1b Nomenclature History
- Previous Names
-
- id:ibd3427
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in brain development; cytoskeleton organization; and intracellular signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoplasm. Is expressed in hindbrain; midbrain; spinal cord; telencephalon; and yolk syncytial layer. Human ortholog(s) of this gene implicated in female breast cancer and mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations. Orthologous to human MAST1 (microtubule associated serine/threonine kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Kudoh et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations | Alliance | Mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations | 618273 |
1 - 1 of 1
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR015022 | Microtubule-associated serine/threonine-protein kinase, pre-PK domain |
1 - 5 of 10 Show all
Domain Details Per Protein
| Protein | Additional Resources | Length | AGC-kinase, C-terminal | Microtubule-associated serine/threonine-protein kinase, catalytic domain | Microtubule-associated serine/threonine-protein kinase, pre-PK domain | Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily | PDZ domain | PDZ superfamily | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine/threonine-protein kinases, AGC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AXQ6 | InterPro | 1634 |
1 - 1 of 1
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mast1b-201
(1)
|
Ensembl | 4,776 nt | ||
| mRNA |
mast1b-202
(1)
|
Ensembl | 7,288 nt | ||
| mRNA |
mast1b-203
(1)
|
Ensembl | 2,310 nt | ||
| mRNA |
mast1b-204
(1)
|
Ensembl | 4,722 nt | ||
| mRNA |
mast1b-205
(1)
|
Ensembl | 4,764 nt |
1 - 5 of 7 Show all
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance